Products for Research Use Only
RegisterLogin

GJB6 Antibody

CAT: 0223-58-181Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-181Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.
NCBI Gene ID
10804
Swiss Prot
O95452
Accession Number
O95452
Host
Rabbit
Reactivity
Human
Immunogen
This GJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human GJB6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
GJB6
NCBI Official Name
Gap junction beta-6 protein
NCBI Organism
Homo sapiens
Background Reference 01
Beltramello, M., et al., Biochem. Biophys. Res. Commun. 305 (4) :1024-1033 (2003) .
Background Reference 02
Common, J.E., et al., Biochem. Biophys. Res. Commun. 298 (5) :651-656 (2002) .
Background Reference 03
Smith, F.J., et al., J. Invest. Dermatol. 118 (3) :530-532 (2002) .
Background Reference 04
Del Castillo, I., et al., N. Engl. J. Med. 346 (4) :243-249 (2002) .
Other Product Names
Gap junction beta-6 protein, Connexin-30, Cx30, GJB6
Tested Applications
WB, IHC-P
Physical Properties
Liquid

Related Products

CatalogName
45-673GJB2 Antibody
28-526GJB1 Antibody
13-436GJB1 Antibody
8031-01GJB2 Antibody
28-527GJB2 Antibody
8031-002mgGJB2 Antibody
8031-01mgGJB2 Antibody
28-530GJB4 Antibody
58-180GJB5 Antibody
33-671Connexin 32 Antibody [GJB1/1753]

Alternative Products

CatalogName
A23183-50UGGJB6 Antibody

Popular Products