GABRA3 Antibody

• Background:

  GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

• NCBI Gene ID:

  2556

• Swiss Prot:

  P34903

• Accession Number:

  NP_000799

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRA3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GABRA3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  55 kDa

• Applications Notes:

  GABRA3 antibody can be used for detection of GABRA3 by ELISA at 1:312500. GABRA3 antibody can be used for detection of GABRA3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  GABRA3

• NCBI Official Name:

  Gamma-aminobutyric acid (GABA) A receptor, alpha 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chou, K.C. et al., (2004) Biochem. Biophys. Res. Commun. 316 (3), 636-642.

• Other Product Names:

  GABRA3

• Tested Applications:

  ELISA, WB

• Protein ID:

  4557603

• Physical Properties:

  Liquid