THRA Antibody

• Background:

  The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.

• NCBI Gene ID:

  7067

• Swiss Prot:

  P10827

• Accession Number:

  NP_003241

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human THRA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store THRA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  55 kDa, 47 kDa

• Applications Notes:

  THRA antibody can be used for detection of THRA by ELISA at 1:62500. THRA antibody can be used for detection of THRA by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  THRA

• NCBI Official Name:

  Thyroid hormone receptor, alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  DeLong, L.J., et al., (2004) J. Biol. Chem. 279 (15), 15356-15367.

• Other Product Names:

  THRA, AR7, EAR7, ERBA, CHNG6, ERBA1, NR1A1, THRA1, THRA2, ERB-T-1, c-ERBA-1

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  20127452

• Physical Properties:

  Liquid