METTL3 Antibody

• Background:

  METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

• NCBI Gene ID:

  56339

• Swiss Prot:

  Q86U44

• Accession Number:

  NP_062826

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human METTL3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1207 - Raji Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store METTL3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  64 kDa

• Applications Notes:

  METTL3 antibody can be used for detection of METTL3 by ELISA at 1:312500. METTL3 antibody can be used for detection of METTL3 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  METTL3

• NCBI Official Name:

  Methyltransferase like 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bujnicki, J.M., et al., (2002) J. Mol. Evol. 55 (4), 431-444.

• Other Product Names:

  METTL3, M6A, IME4, Spo8, MT-A70

• Tested Applications:

  ELISA, WB

• Protein ID:

  21361827

• Physical Properties:

  Liquid