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METTL3 antibody

CAT: 0710-FNab05139Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05139Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Synonyms
N6-adenosine-methyltransferase catalytic subunit|Methyltransferase-like protein 3 (hMETTL3) |N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) |METTL3|MTA70
Gene ID
56339
UniProt
Q86U44
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Methyltransferase like 3
Target
METTL3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IP : 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q86U44

N(6)-adenosine-methyltransferase catalytic subunit METTL3

MTA70_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86U44
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METTL3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.348
Processing
—
Secondary accessions
O14736, Q86V05, Q9HB32
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsDifferentiationDNA damageImmunityInnate immunityOogenesisSpermatogenesis

Cellular component

CytoplasmNucleus

Molecular function

MethyltransferaseRNA-bindingTransferase

Ligand

S-adenosyl-L-methionine

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