TPH2 Antibody

• Background :

  Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT) . 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.

• NCBI Gene ID :

  121278

• Swiss Prot :

  Q8IWU9

• Accession Number :

  NP_775489

• Host :

  Rabbit

• Reactivity :

  Human, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPH2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TPH2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  56 kDa

• Applications Notes :

  TPH2 antibody can be used for detection of TPH2 by ELISA at 1:62500. TPH2 antibody can be used for detection of TPH2 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  TPH2

• NCBI Official Name :

  Tryptophan hydroxylase 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Walther, D.J., et al., (2003) Science 299 (5603), 76.

• Other Product Names :

  TPH2, NTPH, ADHD7

• Tested Applications :

  ELISA, WB

• Protein ID :

  31795563

• Physical Properties :

  Liquid