Products for Research Use Only
RegisterLogin

XRCC5 Antibody

CAT: 0223-28-007Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-28-007Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
NCBI Gene ID
7520
Swiss Prot
Q4VBQ5
Accession Number
NP_066964
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XRCC5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store XRCC5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
83 kDa
Applications Notes
XRCC5 antibody can be used for detection of XRCC5 by ELISA at 1:12500. XRCC5 antibody can be used for detection of XRCC5 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
XRCC5
NCBI Official Name
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
NCBI Organism
Homo sapiens
Background Reference 01
Sawchuk, D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831.
Other Product Names
XRCC5, KU80, KUB2, Ku86, NFIV, KARP1, KARP-1
Tested Applications
ELISA, WB, IHC
Protein ID
10863945
Physical Properties
Liquid

Related Products

CatalogName
45-173PXRCC5 Peptide
16-747XRCC4 Antibody
61-969XRCC1 Antibody
61-787XRCC6 Antibody
18-524XRCC3 Antibody
60-188XRCC4 Antibody
18-186XRCC2 Antibody
15-120XRCC2 Antibody
61-786XRCC6 Antibody
18-234XRCC4 Antibody, KO Validated

Alternative Products

CatalogName
70R-33812XRCC5 antibody

Popular Products