XRCC4 Antibody

• Background:

  The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants.

• NCBI Gene ID:

  7518

• Swiss Prot:

  Q13426

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human XRCC4 (NP_071801.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 55kDa

• Fragment:

  IgG

• Symbol:

  XRCC4

• Positive Control 2:

  MCF7

• Positive Control 3:

  K562

• Positive Control 4:

  HeLa

• Positive Control 5:

  Mouse thymus

• Positive Control 6:

  Mouse heart

• NCBI Official Name:

  DNA repair protein XRCC4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid