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TOX Antibody

CAT: 0223-27-925Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-925Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1; MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1; MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.
NCBI Gene ID
9760
Swiss Prot
O94900
Accession Number
NP_055544
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TOX.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TOX antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
58 kDa
Applications Notes
TOX antibody can be used for detection of TOX by ELISA at 1:312500. TOX antibody can be used for detection of TOX by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TOX
NCBI Official Name
Thymocyte selection-associated high mobility group box
NCBI Organism
Homo sapiens
Background Reference 01
Aliahmad, P., (2004) J. Exp. Med. 199 (8), 1089-1099.
Other Product Names
TOX, KIAA0808, TOX1
Tested Applications
ELISA, WB
Protein ID
7662322
Physical Properties
Liquid

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