STAT4 Antibody

• Background:

  STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

• NCBI Gene ID:

  6775

• Swiss Prot:

  Q14765

• Accession Number:

  NP_003142

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAT4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer, Signal Transduction, Immunology

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store STAT4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  86 kDa

• Applications Notes:

  STAT4 antibody can be used for detection of STAT4 by ELISA at 1:62500. STAT4 antibody can be used for detection of STAT4 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  STAT4

• NCBI Official Name:

  Signal transducer and activator of transcription 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Torpey, N., et al., (2004) J. Biol. Chem. 279 (25), 26789-26796.

• Other Product Names:

  STAT4, SLEB11

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4507255

• Physical Properties:

  Liquid