STAT4 Antibody

• Background :

  STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

• NCBI Gene ID :

  6775

• Swiss Prot :

  Q14765

• Accession Number :

  NP_003142

• Host :

  Rabbit

• Reactivity :

  Human, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STAT4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer, Signal Transduction, Immunology

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store STAT4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  86 kDa

• Applications Notes :

  STAT4 antibody can be used for detection of STAT4 by ELISA at 1:62500. STAT4 antibody can be used for detection of STAT4 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  STAT4

• NCBI Official Name :

  Signal transducer and activator of transcription 4

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Torpey, N., et al., (2004) J. Biol. Chem. 279 (25), 26789-26796.

• Other Product Names :

  STAT4, SLEB11

• Tested Applications :

  ELISA, WB, IHC

• Protein ID :

  4507255

• Physical Properties :

  Liquid