RB1 Antibody

• Background:

  Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.

• NCBI Gene ID:

  5925

• Swiss Prot:

  P06400

• Accession Number:

  NP_000312

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cell Cycle, Cancer, Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1224 - Daudi Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  106 kDa

• Applications Notes:

  RB1 antibody can be used for detection of RB1 by ELISA at 1:312500. RB1 antibody can be used for detection of RB1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  RB1

• NCBI Official Name:

  Retinoblastoma 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dasgupta, P., et al., (2004) Mol. Cell. Biol. 24 (21), 9527-9541.

• Other Product Names:

  RB1, RB, pRb, OSRC, pp110, p105-Rb

• Tested Applications:

  ELISA, WB

• Protein ID:

  108773787

• Physical Properties:

  Liquid