SP140 Antibody

• Background:

  SP140 is the nuclear body protein found specifically in all NP cells. HIV-1 infection induced its partial dispersal from nuclear bodies into cytosolic colocalization with Vif.

• NCBI Gene ID:

  11262

• Swiss Prot:

  Q13342

• Accession Number:

  NP_001005176

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SP140.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1207 - Raji Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SP140 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  20 kDa

• Applications Notes:

  SP140 antibody can be used for detection of SP140 by ELISA at 1:62500. SP140 antibody can be used for detection of SP140 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SP140

• NCBI Official Name:

  SP140 nuclear body protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Madani, N., et al., (2002) J. Virol. 76 (21), 11133-11138.

• Other Product Names:

  SP140, LYSP100, LYSP100-A, LYSP100-B

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  52487277

• Physical Properties:

  Liquid