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NCOR1 Antibody

CAT: 0223-27-612Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-612Size:100 µL
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Background
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
NCBI Gene ID
9611
Swiss Prot
Q86YY0
Accession Number
Q86YY0
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NCOR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10420 - Fetal Small Intestine Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NCOR1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
104 kDa
Applications Notes
NCOR1 antibody can be used for detection of NCOR1 by ELISA at 1:62500. NCOR1 antibody can be used for detection of NCOR1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NCOR1
NCBI Official Name
Nuclear receptor corepressor 1
NCBI Organism
Homo sapiens
Background Reference 01
Horlein, A.J., et al., (1995) Nature 377 (6548), 397-404.
Other Product Names
NCOR1, N-CoR, TRAC1, N-CoR1, hN-CoR
Tested Applications
ELISA, WB
Protein ID
74759545
Physical Properties
Liquid

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