CTBP1 Antibody

• Background:

  CTBP1 binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

• NCBI Gene ID:

  1487

• Swiss Prot:

  Q7Z2Q5

• Accession Number:

  NP_001012632

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CTBP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CTBP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  47 kDa, 48 kDa

• Applications Notes:

  CTBP1 antibody can be used for detection of CTBP1 by ELISA at 1:62500. CTBP1 antibody can be used for detection of CTBP1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CTBP1

• NCBI Official Name:

  C-terminal binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Spyer, M., et al., (2006) Cell Cycle 5 (5), 530-537.

• Other Product Names:

  CTBP1, BARS

• Tested Applications:

  ELISA, WB

• Protein ID:

  61743967

• Physical Properties:

  Liquid