Products for Research Use Only

TBX19 Antibody

CAT: 0223-27-564Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-564Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC) -expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.
NCBI Gene ID
9095
Swiss Prot
O60806
Accession Number
NP_005140
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is supplied as total IgG.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TBX19 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
TBX19 antibody can be used for detection of TBX19 by ELISA at 1:62500. TBX19 antibody can be used for detection of TBX19 by western blot at 1.0-1.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TBX19
NCBI Official Name
T-box 19
NCBI Organism
Homo sapiens
Background Reference 01
Maira, M., et al., (2003) J.Biol.Chem.278 (47), 46523-46532.
Other Product Names
TBX19, TPIT, TBS19, dJ747L4.1
Tested Applications
ELISA, WB, IHC
Protein ID
4827024
Physical Properties
Liquid