MMP19 Antibody

• Background:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19) . Multiple transcript variants encoding distict isoforms have been identified for this gene.

• NCBI Gene ID:

  4327

• Swiss Prot:

  Q99542

• Accession Number:

  NP_002420

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP19.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MMP19 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  56 kDa

• Applications Notes:

  MMP19 antibody can be used for detection of MMP19 by ELISA at 1:62500. MMP19 antibody can be used for detection of MMP19 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MMP19

• NCBI Official Name:

  Matrix metallopeptidase 19

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sadowski, T., et al., (2003) Mol.Biol.Cell14 (11), 4569-4580.

• Other Product Names:

  MMP19, MMP18, RASI-1

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4505213

• Physical Properties:

  Liquid