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SMAD7 Antibody

CAT: 0223-27-478Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-478Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
NCBI Gene ID
4092
Swiss Prot
O15105
Accession Number
NP_005895
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMAD7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
SMAD7 antibody can be used for detection of SMAD7 by ELISA at 1:62500. SMAD7 antibody can be used for detection of SMAD7 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SMAD7
NCBI Official Name
SMAD family member 7
NCBI Organism
Homo sapiens
Background Reference 01
Suh, Y.A., (2006) Biochem. Biophys. Res. Commun. 341 (3), 889-894.
Other Product Names
SMAD7, FLJ16482, MADH7, MADH8, CRCS3
Tested Applications
ELISA, WB
Protein ID
5174517
Physical Properties
Liquid

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