HOXB3 Antibody

• Background:

  This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) .

• NCBI Gene ID:

  3213

• Swiss Prot:

  P14651

• Accession Number:

  P14651

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HOXB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human HOXB3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HOXB3

• NCBI Official Name:

  Homeobox protein Hox-B3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Palakurthy, R.K., et al. Mol. Cell 36 (2) :219-230 (2009)

• Background Reference 02:

  Ferrai, C., et al. Mol. Biol. Cell 20 (15) :3543-3551 (2009)

• Background Reference 03:

  Chung, N., et al. Mol. Biol. Rep. 36 (2) :227-235 (2009)

• Background Reference 04:

  Speleman, F., et al. Leukemia 19 (3) :358-366 (2005)

• Other Product Names:

  Homeobox protein Hox-B3, Homeobox protein Hox-27, Homeobox protein Hox-2G, HOXB3, HOX2G

• Tested Applications:

  WB, IHC-P

• Protein ID:

  215274007

• Physical Properties:

  Liquid