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RACGAP1 Antibody

CAT: 0223-27-437Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-437Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
NCBI Gene ID
29127
Swiss Prot
Q9H0H5
Accession Number
NP_037409
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RACGAP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RACGAP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
71 kDa
Applications Notes
RACGAP1 antibody can be used for detection of RACGAP1 by ELISA at 1:1562500. RACGAP1 antibody can be used for detection of RACGAP1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RACGAP1
NCBI Official Name
Rac GTPase activating protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Niiya, F., et al., (2005) J. Biol. Chem. 280 (43), 36502-36509.
Other Product Names
RACGAP1, CYK4, ID-GAP, HsCYK-4, MgcRacGAP
Tested Applications
ELISA, WB
Protein ID
21361397
Physical Properties
Liquid

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