RACGAP1 Antibody

• Background:

  Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC, and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

• NCBI Gene ID:

  29127

• Swiss Prot:

  Q9H0H5

• Accession Number:

  NP_037409

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RACGAP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction, Immunology

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RACGAP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  71 kDa

• Applications Notes:

  RACGAP1 antibody can be used for detection of RACGAP1 by ELISA at 1:1562500. RACGAP1 antibody can be used for detection of RACGAP1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  RACGAP1

• NCBI Official Name:

  Rac GTPase activating protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Niiya, F., et al., (2005) J. Biol. Chem. 280 (43), 36502-36509.

• Other Product Names:

  RACGAP1, CYK4, ID-GAP, HsCYK-4, MgcRacGAP

• Tested Applications:

  ELISA, WB

• Protein ID:

  21361397

• Physical Properties:

  Liquid