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NR5A1 Antibody

CAT: 0223-27-410Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-410Size:100 µL
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Background
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
2516
Swiss Prot
Q13285
Accession Number
NP_004950
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR5A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR5A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
52 kDa
Applications Notes
NR5A1 antibody can be used for detection of NR5A1 by ELISA at 1:1562500. NR5A1 antibody can be used for detection of NR5A1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR5A1
NCBI Official Name
Nuclear receptor subfamily 5, group A, member 1
NCBI Organism
Homo sapiens
Background Reference 01
Skaletsky, H., Mol. Cell. Biochem. 307 (1-2), 65-71 (2008) .
Other Product Names
NR5A1, AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Tested Applications
ELISA, WB
Protein ID
20070193
Physical Properties
Liquid

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