ESR2 Antibody

CAT: 0223-27-386Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-386Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
NCBI Gene ID
2100
Swiss Prot
Q92731-7
Accession Number
Q92731
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ESR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ESR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa, 55 kDa, 55 kDa, 59 kDa
Applications Notes
ESR2 antibody can be used for detection of ESR2 by ELISA at 1:312500. ESR2 antibody can be used for detection of ESR2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ESR2
NCBI Official Name
Estrogen receptor 2 (ER beta)
NCBI Organism
Homo sapiens
Background Reference 01
Brandenberger, A.W., et al., (1997) J. Clin. Endocrinol. Metab. 82 (10), 3509-3512.
Other Product Names
ESR2, Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA
Tested Applications
ELISA, WB
Protein ID
6166154
Physical Properties
Liquid

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