CREB1 Antibody

• Background :

  CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

• NCBI Gene ID :

  1385

• Swiss Prot :

  P16220

• Accession Number :

  NP_604391

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREB1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer, Signal Transduction

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CREB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  37 kDa

• Applications Notes :

  CREB1 antibody can be used for detection of CREB1 by ELISA at 1:312500. CREB1 antibody can be used for detection of CREB1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CREB1

• NCBI Official Name :

  CAMP responsive element binding protein 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Melnikova, V.O., (2006) J. Biol. Chem. 281 (5), 2911-2922.

• Other Product Names :

  CREB1, CREB, MGC9284

• Tested Applications :

  ELISA, WB

• Protein ID :

  19745184

• Physical Properties :

  Liquid