CREG1 Antibody

• Background:

  The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

• NCBI Gene ID:

  8804

• Swiss Prot:

  O75629

• Accession Number:

  O75629

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CREG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of human CREG1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CREG1

• NCBI Official Name:

  Protein CREG1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Han, Y., et al. J. Mol. Cell. Cardiol. 48 (6) :1225-1235 (2010)

• Background Reference 02:

  Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

• Background Reference 03:

  Han, Y., et al. Exp. Cell Res. 315 (19) :3301-3311 (2009)

• Background Reference 04:

  Bian, Z., et al. J. Cell. Mol. Med. 13 (7) :1302-1313 (2009)

• Other Product Names:

  Protein CREG1, Cellular repressor of E1A-stimulated genes 1, CREG1, CREG

• Tested Applications:

  WB

• Physical Properties:

  Liquid