CREB3 Antibody

• Background:

  CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.

• NCBI Gene ID:

  10488

• Swiss Prot:

  Q5TCV1

• Accession Number:

  NP_006359

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREB3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CREB3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  41 kDa

• Applications Notes:

  CREB3 antibody can be used for detection of CREB3 by ELISA at 1:312500. CREB3 antibody can be used for detection of CREB3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CREB3

• NCBI Official Name:

  CAMP responsive element binding protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Misra, V., et al., (2005) J. Biol. Chem. 280 (15), 15257-15266.

• Other Product Names:

  CREB3, LZIP, LUMAN

• Tested Applications:

  ELISA, WB

• Protein ID:

  22219462

• Physical Properties:

  Liquid