SMARCA5 Antibody

• Background :

  SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• NCBI Gene ID :

  8467

• Swiss Prot :

  O60264

• Accession Number :

  NP_003592

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMARCA5.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Tranfected 293T Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMARCA5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  122 kDa

• Applications Notes :

  SMARCA5 antibody can be used for detection of SMARCA5 by ELISA at 1:312500. SMARCA5 antibody can be used for detection of SMARCA5 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  SMARCA5

• NCBI Official Name :

  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Olsen, J.V., (2006) Cell 127 (3), 635-648.

• Other Product Names :

  SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H

• Tested Applications :

  ELISA, WB

• Protein ID :

  325651836

• Physical Properties :

  Liquid