OPRK1 Antibody

• Background:

  OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.

• NCBI Gene ID:

  4986

• Swiss Prot:

  P41145

• Accession Number:

  NP_000903

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OPRK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction, Immunology

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OPRK1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Applications Notes:

  OPRK1 antibody can be used for detection of OPRK1 by ELISA at 1:62500. OPRK1 antibody can be used for detection of OPRK1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  OPRK1

• NCBI Official Name:

  Opioid receptor, kappa 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Edenberg, H.J., (2008) Hum. Mol. Genet. 17 (12), 1783-1789.

• Other Product Names:

  OPRK1, KOR, OPRK, KOR-1, K-OR-1

• Tested Applications:

  ELISA, WB

• Protein ID:

  39725940

• Physical Properties:

  Liquid