OPRK1 Antibody

• Background:

  Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

• NCBI Gene ID:

  4986

• Swiss Prot:

  P41145

• Accession Number:

  P41145

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This OPRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human OPRK1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  OPRK1

• NCBI Official Name:

  Kappa-type opioid receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

• Background Reference 02:

  Bruijnzeel, A.W. Brain Res Rev 62 (1) :127-146 (2009)

• Background Reference 03:

  Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

• Background Reference 04:

  De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)

• Other Product Names:

  Kappa-type opioid receptor, K-OR-1, KOR-1, OPRK1, OPRK

• Tested Applications:

  WB

• Protein ID:

  116242691

• Physical Properties:

  Liquid