CDK5 Antibody

• Background:

  CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase.

• NCBI Gene ID:

  1020

• Swiss Prot:

  Q00535

• Accession Number:

  NP_004926

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDK5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cell Cycle, Cancer, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDK5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  33 kDa

• Applications Notes:

  CDK5 antibody can be used for detection of CDK5 by ELISA at 1:62500. CDK5 antibody can be used for detection of CDK5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CDK5

• NCBI Official Name:

  Cyclin-dependent kinase 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, R., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7570-7575.

• Other Product Names:

  CDK5, PSSALRE

• Tested Applications:

  ELISA, WB

• Protein ID:

  4826675

• Physical Properties:

  Liquid