CDC42EP5 Antibody

• Background:

  CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.

• NCBI Gene ID:

  148170

• Swiss Prot:

  Q6NZY7

• Accession Number:

  NP_659494

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDC42EP5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Tranfected 293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDC42EP5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  15 kDa

• Applications Notes:

  CDC42EP5 antibody can be used for detection of CDC42EP5 by ELISA at 1:312500. CDC42EP5 antibody can be used for detection of CDC42EP5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CDC42EP5

• NCBI Official Name:

  CDC42 effector protein (Rho GTPase binding) 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Joberty, G., (2001) Nat. Cell Biol. 3 (10), 861-866.

• Other Product Names:

  CDC42EP5, Borg3, CEP5, MGC21945, MGC71153

• Tested Applications:

  ELISA, WB

• Protein ID:

  30089966

• Physical Properties:

  Liquid