PCDHA5 Antibody

CAT: 0223-26-395Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-395Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
NCBI Gene ID
56143
Swiss Prot
Q9Y5H7
Accession Number
NP_061731
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCDHA5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
99 kDa
Applications Notes
PCDHA5 antibody can be used for detection of PCDHA5 by ELISA at 1:312500. PCDHA5 antibody can be used for detection of PCDHA5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PCDHA5
NCBI Official Name
Protocadherin alpha 5
NCBI Organism
Homo sapiens
Background Reference 01
Schmutz, J., (2004) Nature 431 (7006), 268-274.
Other Product Names
PCDHA5, CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Tested Applications
ELISA, WB
Protein ID
9256590
Physical Properties
Liquid

Related Products

CatalogName
56-182PCDHA8 Antibody
56-254PCDHA9 Antibody
56-933PCDHB5 Antibody
59-719PCDHA1 Antibody
56-243PCDHA3 Antibody
59-723PCDHA2 Antibody
58-269PCDHA4 Antibody
30-579PCDH15 Antibody
19-489PCDHA6 Antibody
59-843PCDHGA5 Antibody

Alternative Products

CatalogName
C50422-01PCDHA5 Antibody
A15316-1Anti-PCDHA5 Antibody
MBS9215157-01PCDHA5 Antibody (Center)
MBS9233959-01PCDHA5 Polyclonal Antibody
TA331059PCDHA5 Rabbit Polyclonal Antibody
OAAB08247-400ULPCDHA5 Antibody - middle region
NBP1-92244Rabbit Polyclonal PCDHA5 Antibody
SL11119R-01Rabbit Anti-PCDHA5 antibody
MBS9218791-01PCDHA5 Antibody (Center) Blocking peptide
abx114897Protocadherin Alpha 5 (PCDHA5) Antibody

Popular Products