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PCDH15 Antibody

CAT: 0223-30-579Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-30-579Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
NCBI Gene ID
65217
Swiss Prot
A2A3E5
Accession Number
CAM15122
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDH15.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCDH15 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
80 kDa
Applications Notes
PCDH15 antibody can be used for detection of PCDH15 by ELISA at 1:62500. PCDH15 antibody can be used for detection of PCDH15 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PCDH15
NCBI Official Name
Protocadherin-related 15
NCBI Organism
Homo sapiens
Other Product Names
PCDH15, RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Tested Applications
ELISA, WB
Protein ID
123221579
Physical Properties
Liquid

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