PCDH15 Antibody

• Background:

  PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

• NCBI Gene ID:

  65217

• Swiss Prot:

  A2A3E5

• Accession Number:

  CAM15122

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDH15.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCDH15 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  80 kDa

• Applications Notes:

  PCDH15 antibody can be used for detection of PCDH15 by ELISA at 1:62500. PCDH15 antibody can be used for detection of PCDH15 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PCDH15

• NCBI Official Name:

  Protocadherin-related 15

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PCDH15, RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15

• Tested Applications:

  ELISA, WB

• Protein ID:

  123221579

• Physical Properties:

  Liquid