CMAS Antibody

CAT: 0223-26-355Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-355Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
NCBI Gene ID
55907
Swiss Prot
Q8NFW8
Accession Number
NP_061156
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CMAS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CMAS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
CMAS antibody can be used for detection of CMAS by ELISA at 1:12500. CMAS antibody can be used for detection of CMAS by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CMAS
NCBI Official Name
Cytidine monophosphate N-acetylneuraminic acid synthetase
NCBI Organism
Homo sapiens
Background Reference 01
Kutsenko, A.S., (2002) Nucleic Acids Res. 30 (14), 3163-3170.
Other Product Names
CMAS, CSS
Tested Applications
ELISA, WB
Protein ID
8923900
Physical Properties
Liquid

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