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GATM Antibody

CAT: 0223-26-325Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-325Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GATM is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
2628
Swiss Prot
P50440
Accession Number
NP_001473
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GATM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GATM antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
44 kDa
Applications Notes
GATM antibody can be used for detection of GATM by ELISA at 1:62500. GATM antibody can be used for detection of GATM by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GATM
NCBI Official Name
Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
NCBI Organism
Homo sapiens
Background Reference 01
Kawasaki, H., (2006) Neurology 67 (9), 1713-1714.
Other Product Names
GATM, AGAT, AT, CCDS3
Tested Applications
ELISA, WB
Protein ID
4503933
Physical Properties
Liquid

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