NDE1 Antibody

CAT: 0223-26-262Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-262Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
NDE1 is required for centrosome duplication and formation and function of the mitotic spindle. It is essential for the development of the cerebral cortex. NDE1 may regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex
NCBI Gene ID
54820
Swiss Prot
Q9NXR1-2
Accession Number
NP_060138
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NDE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NDE1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
NDE1 antibody can be used for detection of NDE1 by ELISA at 1:62500. NDE1 antibody can be used for detection of NDE1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NDE1
NCBI Official Name
NudE neurodevelopment protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Burdick, K.E., (er) Hum. Mol. Genet. (2008) In press.
Other Product Names
NDE1, FLJ20101, HOM-TES-87, NUDE, NUDE1, NDE, LIS4
Tested Applications
ELISA, WB
Protein ID
8923110
Physical Properties
Liquid

Related Products

CatalogName
46-929NDEL1 Antibody
46-929PNDEL1 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
22-741COMMD1 Antibody
22-755ADPGK Antibody
22-760DZIP3 Antibody
22-766MAG Antibody
22-776MCM10 Antibody

Alternative Products

CatalogName
FNab05600NDE1 antibody

Popular Products