RegisterLogin

PTPRE Antibody

CAT: 0223-26-157Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-157Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
NCBI Gene ID
5791
Swiss Prot
P23469
Accession Number
NP_006495
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTPRE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PTPRE antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
81 kDa
Applications Notes
PTPRE antibody can be used for detection of PTPRE by ELISA at 1:312500. PTPRE antibody can be used for detection of PTPRE by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PTPRE
NCBI Official Name
Protein tyrosine phosphatase, receptor type, E
NCBI Organism
Homo sapiens
Background Reference 01
Weiss, B. (2008) J. Biol. Chem. 283 (8), 4612-4621.
Other Product Names
PTPRE, DKFZp313F1310, HPTPE, PTPE, R-PTP-EPSILON
Tested Applications
ELISA, WB
Protein ID
5729993
Physical Properties
Liquid

Related Products

CatalogName
15-451PTPRG Antibody
18-424PTPRA Antibody
57-787PTPRN Antibody
XW-7816PTPRF Antibody
46-702PTPRH Antibody
XW-7814PTPRC Antibody
42-745PTPRN Antibody
48-181PTPRM Antibody
23-609PTPRU Antibody
18-513PTPRC Antibody

Alternative Products

CatalogName
C45726-01PTPRE Antibody

Popular Products