GCS1 Antibody

• Background:

  GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.

• NCBI Gene ID:

  7841

• Swiss Prot:

  Q13724

• Accession Number:

  NP_006293

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GCS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GCS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  92 kDa

• Applications Notes:

  GCS1 antibody can be used for detection of GCS1 by ELISA at 1:312500. GCS1 antibody can be used for detection of GCS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MOGS

• NCBI Official Name:

  Mannosyl-oligosaccharide glucosidase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hardt, B., (2003) Glycobiology 13 (3), 159-168.

• Other Product Names:

  GCS1, DER7, GCS1, CDG2B, CWH41

• Tested Applications:

  ELISA, WB

• Protein ID:

  149999606

• Physical Properties:

  Liquid