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DEGS1 Antibody

CAT: 0223-26-055Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-055Size:100 µL
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Background
DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
NCBI Gene ID
8560
Swiss Prot
O15121
Accession Number
NP_003667
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEGS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DEGS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
DEGS1 antibody can be used for detection of DEGS1 by ELISA at 1:312500. DEGS1 antibody can be used for detection of DEGS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DEGS1
NCBI Official Name
Delta (4) -desaturase, sphingolipid 1
NCBI Organism
Homo sapiens
Background Reference 01
Kraveka, J.M., (2007) J. Biol. Chem. 282 (23), 16718-16728.
Other Product Names
DEGS1, DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
Tested Applications
ELISA, WB
Protein ID
4505193
Physical Properties
Liquid

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