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UBE3B Antibody

CAT: 0223-25-857Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-857Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE3B is a member of the E3 ubiquitin-conjugating enzyme family. UBE3B may interact with other proteins and play a role in stress response.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family. The encoded protein may interact with other proteins and play a role in stress response. Alternatively spliced transcript variants encoding the same protein isoform have been identified for this gene.
NCBI Gene ID
89910
Swiss Prot
Q7Z3V4
Accession Number
NP_569733
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Homeostasis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UBE3B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
123 kDa
Applications Notes
UBE3B antibody can be used for detection of UBE3B by ELISA at 1:312500. UBE3B antibody can be used for detection of UBE3B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
UBE3B
NCBI Official Name
Ubiquitin protein ligase E3B
NCBI Organism
Homo sapiens
Background Reference 01
Szafranski, K., Genome Biol. 8 (8), R154 (2007) .
Other Product Names
UBE3B, DKFZp586K2123, DKFZp686A1051, FLJ45294, MGC131858, MGC78388, BPIDS
Tested Applications
ELISA, WB
Protein ID
35493959
Physical Properties
Liquid

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