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UBE2B Antibody

CAT: 0223-61-079Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-079Size:400 µL
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Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
NCBI Gene ID
7320
Swiss Prot
P63146
Accession Number
P63146
Host
Rabbit
Reactivity
Human
Immunogen
This UBE2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the C-terminal region of human UBE2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Bovine, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Symbol
UBE2B
NCBI Official Name
Ubiquitin-conjugating enzyme E2 B
NCBI Organism
Homo sapiens
Background Reference 01
Koken, M.H., et al., Genomics 12 (3) :447-453 (1992) .
Background Reference 02
Koken, M.H., et al., Proc. Natl. Acad. Sci. U.S.A. 88 (20) :8865-8869 (1991) .
Background Reference 03
Schneider, R., et al., EMBO J. 9 (5) :1431-1435 (1990) .
Other Product Names
Ubiquitin-conjugating enzyme E2 B, RAD6 homolog B, HR6B, hHR6B, Ubiquitin carrier protein B, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-protein ligase B, UBE2B, RAD6B
Tested Applications
WB, IHC-P
Protein ID
52783814
Physical Properties
Liquid

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