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FBXO7 antibody

CAT: 0710-FNab03049Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03049Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Synonyms
F-box only protein 7|FBXO7|FBX7
Gene ID
25793
UniProt
Q9Y3I1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
F-box protein 7
Target
FBXO7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58.5 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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