AMOTL1 Antibody

• Background:

  AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.

• NCBI Gene ID:

  154810

• Swiss Prot:

  Q8IY63

• Accession Number:

  NP_570899

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMOTL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store AMOTL1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  106 kDa

• Applications Notes:

  AMOTL1 antibody can be used for detection of AMOTL1 by ELISA at 1:312500. AMOTL1 antibody can be used for detection of AMOTL1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  AMOTL1

• NCBI Official Name:

  Angiomotin like 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mehrle, A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006) .

• Other Product Names:

  AMOTL1, JEAP

• Tested Applications:

  ELISA, WB

• Protein ID:

  22027646

• Physical Properties:

  Liquid