GTSE1 Antibody

• Background:

  GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

• NCBI Gene ID:

  51512

• Swiss Prot:

  Q9NYZ3

• Accession Number:

  NP_057510

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTSE1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GTSE1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  76 kDa

• Applications Notes:

  GTSE1 antibody can be used for detection of GTSE1 by ELISA at 1:62500. GTSE1 antibody can be used for detection of GTSE1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  GTSE1

• NCBI Official Name:

  G-2 and S-phase expressed 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292.

• Other Product Names:

  GTSE1, B99

• Tested Applications:

  ELISA, WB

• Protein ID:

  253970412

• Physical Properties:

  Liquid