ARNTL2 Antibody

• Background:

  ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.

• NCBI Gene ID:

  56938

• Swiss Prot:

  Q8WYA1

• Accession Number:

  NP_064568

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARNTL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1219 - MCF7 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ARNTL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  71 kDa

• Applications Notes:

  ARNTL2 antibody can be used for detection of ARNTL2 by ELISA at 1:1562500. ARNTL2 antibody can be used for detection of ARNTL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ARNTL2

• NCBI Official Name:

  Aryl hydrocarbon receptor nuclear translocator-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shi, J., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press.

• Other Product Names:

  ARNTL2, BMAL2, CLIF, MGC149671, MGC149672, MOP9, PASD9, bHLHe6

• Tested Applications:

  ELISA, WB

• Protein ID:

  31745180

• Physical Properties:

  Liquid