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KCNH7 Antibody

CAT: 0223-25-266Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-266Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH7 is a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
NCBI Gene ID
90134
Swiss Prot
Q8IV15
Accession Number
NP_775185
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNH7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCNH7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
83 kDa
Applications Notes
KCNH7 antibody can be used for detection of KCNH7 by ELISA at 1:62500. KCNH7 antibody can be used for detection of KCNH7 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KCNH7
NCBI Official Name
Potassium voltage-gated channel, subfamily H (eag-related), member 7
NCBI Organism
Homo sapiens
Background Reference 01
Martinez, A., (er) Eur. J. Hum. Genet. (2008) In press.
Other Product Names
KCNH7, ERG3, HERG3, Kv11.3, MGC45986
Tested Applications
ELISA, WB
Protein ID
27886665
Physical Properties
Liquid

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