TIPARP Antibody

• Background:

  TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

• NCBI Gene ID:

  25976

• Swiss Prot:

  Q7Z3E1

• Accession Number:

  NP_056323

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIPARP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TIPARP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  76 kDa

• Applications Notes:

  TIPARP antibody can be used for detection of TIPARP by ELISA at 1:312500. TIPARP antibody can be used for detection of TIPARP by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TIPARP

• NCBI Official Name:

  TCDD-inducible poly (ADP-ribose) polymerase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mehrle, A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006) .

• Other Product Names:

  TIPARP, DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, ARTD14, pART14

• Tested Applications:

  ELISA, WB

• Protein ID:

  38524594

• Physical Properties:

  Liquid