MTO1 Antibody

• Background:

  This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  25821

• Swiss Prot:

  Q9Y2Z2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 420-680 of human MTO1 (NP_036255.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Raji

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 80kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MTO1

• Positive Control 2:

  HeLa

• Positive Control 3:

  MCF7

• Positive Control 4:

  Mouse kidney

• Positive Control 5:

  Mouse heart

• NCBI Official Name:

  Mitochondrial tRNA translation optimization 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MTO1, COXPD10, CGI-02, Homolog of yeast Mto1, Mitochondrial MTO1-3

• Tested Applications:

  WB

• Physical Properties:

  Liquid