MTOR Antibody

• Background:

  The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

• NCBI Gene ID:

  2475

• Swiss Prot:

  P42345

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human mTOR (NP_004949.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Autophagy, Cancer, Cell Cycle, Immunology, Obesity, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 289kDa

• Fragment:

  IgG

• Symbol:

  MTOR

• Positive Control 2:

  K-562

• Positive Control 3:

  U-87MG

• NCBI Official Name:

  Mechanistic target of rapamycin

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TOR Antibody: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, FRAP, FK506-binding protein 12-rapamycin complex-associated protein 1, mTOR

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid