CNOT7 Antibody

• Background:

  The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

• NCBI Gene ID:

  29883

• Swiss Prot:

  Q9UIV1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 33kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  CNOT7

• Positive Control 2:

  U-87MG

• Positive Control 3:

  HT-29

• Positive Control 4:

  Raji

• Positive Control 5:

  HeLa

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  CCR4-NOT transcription complex, subunit 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CNOT7, CAF1, Caf1a, hCAF-1

• Tested Applications:

  WB

• Physical Properties:

  Liquid