CNOT7 Antibody

• Background :

  The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

• NCBI Gene ID :

  29883

• Swiss Prot :

  Q9UIV1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  22Rv1

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 33kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:200 - 1:2000

• Symbol :

  CNOT7

• Positive Control 2 :

  U-87MG

• Positive Control 3 :

  HT-29

• Positive Control 4 :

  Raji

• Positive Control 5 :

  HeLa

• Positive Control 6 :

  Mouse lung

• NCBI Official Name :

  CCR4-NOT transcription complex, subunit 7

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CNOT7, CAF1, Caf1a, hCAF-1

• Tested Applications :

  WB

• Physical Properties :

  Liquid