AURKC Antibody

• Background :

  This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  6795

• Swiss Prot :

  Q9UQB9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human AURKC

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 36kDa

• Fragment :

  IgG

• Symbol :

  AURKC

• Positive Control 2 :

  293T

• Positive Control 3 :

  SW620

• Positive Control 4 :

  BT-474

• Positive Control 5 :

  Mouse testis

• Positive Control 6 :

  Mouse ovary

• NCBI Official Name :

  Aurora kinase C

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  AURKC, STK13, serine/threonine kinase 13 (aurora/IPL1-like), aurora-C, aurora/IPL1-related kinase 3, aurora/IPL1/EG2 protein 2, aurora kinase C, AurC, ARK3, AIK3, AIE2, AIRK3

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid