GNB1L Antibody

• Background:

  This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.

• NCBI Gene ID:

  54584

• Swiss Prot:

  Q9BYB4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human GNB1L (NP_443730.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 35kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  GNB1L

• Positive Control 2:

  MCF7

• Positive Control 3:

  SW620

• Positive Control 4:

  A-549

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse heart

• NCBI Official Name:

  Guanine nucleotide binding protein (G protein), beta polypeptide 1-like

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GNB1L, GY2, FKSG1, WDR14, WDVCF, DGCRK3

• Tested Applications:

  WB

• Physical Properties:

  Liquid